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Image Search Results
Journal: Oncology
Article Title: Certain imidazotetrazines escape O6-methylguanine-DNA methyltransferase and mismatch repair.
doi: 10.1159/000327837
Figure Lengend Snippet: Fig. 2. a Time course of DNA excision repair in SNB19V cells fol- lowing damage by TMZ and methyl ester analog 11 . SNB19V cells were treated with 50 M TMZ and 100 M analog 11 for 2 h, fol- lowed by incubation in fresh media. Samples were taken at indi- cated time points and analyzed by alkaline comet assay. Untreat- ed cells were set as a control. Values are mean 8 SD of triplicate experiments. Strand-break formation by DNA excision repair in SNB19V cells initiated by TMZ and analog 11 was measured as tail moment. The tail moment value of untreated cells was set as
Article Snippet:
Techniques: Incubation, Alkaline Single Cell Gel Electrophoresis, Control